Poor aqueous solubility of carbamazepine
(API) is a persistent problem since many years.
This issue
is prominently relevant to Biopharmaceutics Classification System (BCS) Class
II and Class IV drugs.
Currently we are working to resolve this issue by using the
complexation approach using a novel source Fulvic acid.
Although FA
has been used for solubility enhancement, but our novel sourced fulvic acid which is
purer, cheaper and low on contaminants is yet to be exploited as a
pharmaceutical excipient with improved functionality.
So, the
novelty of this idea relies in the fact that our novel sourced
fulvic acid is explored for its pharmaceutical potential.
Further the our developed complex is characterized physically on the basis of DSC,
FTIR and XRD studies
with the pure drug and complexed
drug.
The results are outstanding!
Authored by:
Rahmuddin Khan
Dept. of Pharmaceutics,
School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi- 110053
Contact me through my blog.
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